Informazioni di General Pharmacology And Toxicology And Pharmacogenomics - Mod I

Dipartimento: Scienze Matematiche, Fisiche E Naturali
Codice di verbalizzazione: 8066716
Metodi di insegnamento: Frontale
Metodi di valutazione: Orale
Prerequisiti: Is necessary for the student to have the fundamental concepts of basic subjects, with particular regard to Anatomy, Physiology, Biochemistry and Molecular Biology. Students should also possess a good knowledge of written and spoken English (B2 level).
Obiettivi: Students will learn the main examples already implemented in clinical practice of Principles of pharmacokinetics: routes of administration and absorption of drugs. Distribution, biotransformation and excretion of drugs. Drug interactions. Principles of pharmacodynamics: drug-receptor interaction, agonists and antagonists, allosteric modulators. Classification of receptors, adaptive responses to drugs. Mechanisms underlying signal transduction pathways. Voltage- dependent and voltage-independent ion channels. Intercellular transmission: glutamate, GABA, acetylcholine, catecholamines, serotonin, nitric oxide, cannabinoids, opioid peptides. Basic principles of normal and pathological synaptic plasticity. Principles of cellular and molecular toxicology. Drug addiction. Pharmacogenomics biomarkers, evaluating their clinical validity and clinical utility and related regulatory issues. Another aim will be to understand the role of pharmacogenetics in the development of new drugs.

Nome classe: MANGO-8067459-GENERAL_AND_MOLECULAR_PHARMACOLOGY_AND_TOXICOLOGY
Link Microsoft Teams: Link
Docente: MANGO DALILA

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