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Maria Gabriella De Martino
maria.gabriella.de.martino@uniroma2.it
Biography: Born in Rome in 1972, I got my Master Deegre in Chemistry and Pharmaceutical Technologies and the PhD in Pharmaceutical Sciences from the University of Rome “La Sapienza”. After 4 years in the USA at the National Institute of Health (NIH) working as Research Fellow I moved back to Italy and I spent 4 years at the Department of Pharmaceutical Studies at the University of Rome “La Sapienza” as part of the “Rientro dei Cervelli” program. In 2009 I joined the University of Rome “Torvergata” where I actually work a lecturer in Pharmaceutical Chemistry at the Deegre Course of Farmacy and I’m involved is several research projects as synthetic chemist.
Title of teaching module: Pharmaceutical and Toxicological Chemistry 1
Description of teaching module (teaching program):
DRUG DESIGN AND DEVELOPMENT Identify target disease, Identify drug target, Establish testing procedures, Find a lead compound, Structure Activity Relationships (SAR), Identify a pharmacophore, Drug design- optimising target interactions, Drug design - optimising pharmacokinetic properties, Toxicological and safety tests
PHARMACOKINETICS Drug Absorption, Distribution; Metabolism Phase I and Phase II Reactions, Cytochrome P450 enzymes, Drug-drug interactions, Drug-food interactions; Excretion; Administration Oral Administration, Inhalation - Respiratory System, Injection, Topical administration (transdermal absorption), Blood level concentrations of drugs; Drug Delivery
SELECTED TOPICS IN MEDICINAL CHEMISTRY ANTI-BACTERIAL AGENTS: Penicillins; Cephalosporins; Monobactam; Carbapenems; ï¢-Lactamase Inhibitors; Glycopeptides; Cycloserine; Fosfomycin; Lipopeptides; Aminoglycosides; Tetracyclines And Glycylcyclines; Macrolides And Ketolides; Lincosamides; Streptogramins; Chloramphenicol; Oxazolidinones; Sulfonamides; Fluoroquinolones; Polymyxins; Bacitracin; Metronidazole.
Anti-Mycobacterial Agents: Isoniazid; Rifamycins; Pyrazinamide; Ethambutol; Ethionamide; Clofazimine; Dapsone.
Antifungal Agents: Amphotericin B; Flucytosine; Imidazoles And Triazoles; Echinocandins; Griseofulvin; Terbinafine; Nystatin.
Antiviral Drugs (Non-Retroviral): Anti-Herpesvirus, Anti-Influenza And Anti-Hepatitis Virus Agents.
Anti-Retroviral Drugs: Nucleoside And Nucleotide Reverse Transcriptase Inhibitors; Non-Nucleoside Reverse Transcriptase Inhibitors; Protease Inhibitors; Entry Inhibitors; Integrase Inhibitors.
Antiprotozoal Drugs: Metronidazole; Pentamidine; Eflornithine; Suramin; Melalsoprol; Miltefosine; Nifurtimox And Benznidazole; Sodium Stibogluconate; Antimalarial Agents: Artemisinin And Derivatives; Atovaquone; Pyrimethamine; Proguanil; Quinolines.
Antihelminthic Drugs: Benzimidazoles; Diethylcarbamazine; Ivermectin; Praziquantel; Pyrantel Pamoate.
Nome del Corso | Facoltà | Anno | ||
---|---|---|---|---|
0 | Pharmaceutical Technologies | Scienze Matematiche, Fisiche E Naturali | 2023/2024 | |
Modulo: Pharmaceutical Technologies - Mod Ii | Scienze Matematiche, Fisiche E Naturali | 2023/2024 | ||
0 | Pharmaceutical Technology With Pharmaceutical Compounding Practices | Scienze Matematiche, Fisiche E Naturali | 2023/2024 | |
Modulo: Pharmaceutical Technology With Pharmaceutical Compounding Practices Mod. Ii | Scienze Matematiche, Fisiche E Naturali | 2023/2024 | ||
0 | Pharmaceutical Technologies | Scienze Matematiche, Fisiche E Naturali | 2022/2023 | |
Modulo: Pharmaceutical Technologies - Mod Ii | Scienze Matematiche, Fisiche E Naturali | 2022/2023 | ||
0 | Pharmaceutical Technologies | Scienze Matematiche, Fisiche E Naturali | 2021/2022 | |
Modulo: Pharmaceutical Technologies - Mod Ii | Scienze Matematiche, Fisiche E Naturali | 2021/2022 | ||
0 | Pharmaceutical Technologies | Scienze Matematiche, Fisiche E Naturali | 2020/2021 | |
Modulo: Pharmaceutical Technologies - Mod Ii | Scienze Matematiche, Fisiche E Naturali | 2020/2021 | ||
0 | Pharmaceutical Technologies | Scienze Matematiche, Fisiche E Naturali | 2019/2020 | |
Modulo: Pharmaceutical Technologies - Mod Ii | Scienze Matematiche, Fisiche E Naturali | 2019/2020 | ||
0 | Pharmaceutical Technologies | Scienze Matematiche, Fisiche E Naturali | 2018/2019 | |
Modulo: Pharmaceutical Technologies - Mod Ii | Scienze Matematiche, Fisiche E Naturali | 2018/2019 | ||
0 | Pharmaceutical Technologies | Scienze Matematiche, Fisiche E Naturali | 2017/2018 | |
Modulo: Pharmaceutical Technologies - Mod Ii | Scienze Matematiche, Fisiche E Naturali | 2017/2018 | ||
0 | Pharmaceutical Technologies | Scienze Matematiche, Fisiche E Naturali | 2016/2017 | |
Modulo: Pharmaceutical Technologies - Mod Ii | Scienze Matematiche, Fisiche E Naturali | 2016/2017 |