Michela Biancolella

MICHELA BIANCOLELLA 

 Department of Biology, Tor Vergata University of Rome, 00133 Rome, Italy

 Laboratory of Medical Genetics, Tor Vergata Hospital, Rome, Italy.

   michela.biancolella@uniroma2.it

WORK EXPERIENCE

From November 2019 to present

Associate Professor of medical genetics, University of Rome “Tor Vergata” .

From March 2019 to present

Assistance activity as a s biologist at the UOC Medical Genetics Laboratory Policlinico Tor Vergata.

June-September 2017                                          

Visiting Researcher at Cedars-Sinai Medical Center Los Angeles, California

From November 2012 to October 2019

Assistant Professor (Medical Genetics) University of Rome "Tor Vergata".

2008-2012       

Research Associate University of Southern California (USC) -Los Angeles,CA  Field of Study: Medical  Genetics

2007-2008

Postdoctoral Fellow University of Rome “Tor Vergata” Field of Study: Molecular Genetics

EDUCATION AND TRAINING                                                                             

2012    

Postgraduate Specialization in Medical Genetics University of Rome “Tor Vergata” (Dissertation of a thesis in Oncogenetics)

2007    

PhD in Advanced Technologies in Biomedicine, University of Rome “Tor Vergata” (Dissertation of a thesis in Medical Genetics

2004    

Qualification for the Biologist profession  University of Tuscia, Viterbo

2003     Degree in Biology, University of “Roma 3” Rome, Italy (Dissertation of a thesis in Molecular Genetics.

PERSONAL SKILLS      

Mother tongue(s)           ITALIAN

Other language(s)         English

High experience in Teaching (at degree and Masters level)

Microsoft Office programs.

Excellent experience in High through Genomic Analysis

RESEARCH AREA: Research activity in the field of molecular genetics with particular reference to the study of gene expression and genomic rearrangements for the understanding of the pathogenetic mechanisms of hereditary and multifactorial diseases; Personalized Medicine.

  PUBLICATIONS ( last 5year)          

Novelli G, Cassadonte C, Sbraccia P, Biancolella M. Genetics: A Starting Point for the Prevention and the Treatment of Obesity. Nutrients. 2023 Jun 17;15(12):2782. doi: 10.3390/nu15122782. PMID: 37375686; PMCID: PMC10305006.

Biancolella M, Colona VL, Luzzatto L, Watt JL, Mattiuz G, Conticello SG, Kaminski N, Mehrian-Shai R, Ko AI, Gonsalves GS,Vasiliou V, Novelli G, Reichardt JKV. COVID-19 annual update: a narrative review. Hum Genomics. 2023 Jul 24;17(1):68. doi: 10.1186/s40246-023-00515-2. PMID: 37488607; PMCID: PMC10367267.

Novelli G, Biancolella M. COVID-19 and Molecular Genetics. Genes (Basel). 2022 Apr 12;13(4):676.

Biancolella M, Colona VL, Mehrian-Shai R, Watt JL, Luzzatto L, Novelli G, Reichardt JKV. COVID-19 2022 update: transition of the pandemic to the endemic phase. Hum Genomics. 2022 Jun 1;16(1):19. doi: 10.1186/s40246-022-00392-1. PMID: 35650595; PMCID: PMC9156835.

Centofanti F, Alonzi T, Latini A, Spitalieri P, Murdocca M, Chen X, Cui W, Shang Q, Goletti D, Shi Y, Duranti A, Tomino C, Biancolella M, Sangiuolo F, Capobianchi MR, Jain S, Novelli G, Pandolfi PP. Indole-3-carbinol in vitro antiviral activity against SARS-Cov-2 virus and in vivo toxicity. Cell Death Discov. 2022 Dec 15;8(1):491. doi: 10.1038/s41420-022-01280-2. PMID: 36522315; PMCID: PMC9751508.

Novelli G, Liu J, Biancolella M, Alonzi T, Novelli A, Patten JJ, Cocciadiferro D, Agolini E, Colona VL, Rizzacasa B, Giannini R, Bigio B, Goletti D, Capobianchi MR, Grelli S, Mann J, McKee TD, Cheng K, Amanat F, Krammer F, Guarracino A, Pepe G, Tomino C, Tandjaoui-Lambiotte Y, Uzunhan Y, Tubiana S, Ghosn J; COVID Human Genetic Effort; French COVID Cohort Study Group; CoV-Contact Cohort, Notarangelo LD, Su HC, Abel L, Cobat A, Elhanan G, Grzymski JJ, Latini A, Sidhu SS, Jain S, Davey RA, Casanova JL, Wei W, Pandolfi PP. Inhibition of HECT E3 ligases as potential therapy for COVID-19. Cell Death Dis. 2021 Mar 24;12(4):310.

Novelli G, Biancolella M, Mehrian-Shai R, Colona VL, Brito AF, Grubaugh ND, Vasiliou V, Luzzatto L, Reichardt JKV. COVID-19 one year into the pandemic: from genetics and genomics to therapy, vaccination, and policy. Hum Genomics. 2021 May 10;15(1):27.

 Biancolella M, Testa B, Baghernajad Salehi L, D'Apice MR, Novelli G. Genetics and Genomics of Breast Cancer: update and translational perspectives. Semin Cancer Biol. 2021 Jul;72:27-35.

Colona VL, Biancolella M, Novelli A, Novelli G. Will GWAS eventually allow the identification of genomic biomarkers for COVID-19 severity and mortality? J Clin Invest. 2021 Dec 1;131(23):e155011.

Biancolella M, Ouédraogo NLM, Zongo N, Zohoncon TM, Testa B, Rizzacasa B, Latini A, Conte C, Compaore TR, Ouedraogo CMR, Traore SS, Simpore J, Novelli G. Breast cancer in West Africa: molecular analysis of BRCA genes in early-onset breast cancer patients in Burkina Faso. Hum Genomics. 2021 Oct 30;15(1):65.

Novelli G, Biancolella M, Latini A, Spallone A, Borgiani P, Papaluca M.  Precision Medicine in Non-Communicable Diseases. High Throughput. 2020 Feb 7;9(1):3.

Latini A, Agolini E, Novelli A, Borgiani P, Giannini R, Gravina P, Smarrazzo A, Dauri M, Andreoni M, Rogliani P, Bernardini S, Helmer-Citterich M, Biancolella M, Novelli G. COVID-19 and Genetic Variants of Protein Involved in the SARS-CoV-2 Entry into the Host Cells. Genes (Basel). 2020 Aug 27;11(9):1010.

Novelli A, Andreani M, Biancolella M , Liberatoscioli L, Passarelli C, Colona VL, Rogliani P, Leonardis F, Campana A, Carsetti R, Andreoni , Bernardini , Novelli G, Locatelli F. HLA allele frequencies and susceptibility to COVID-19 in a group of 99 Italian patients. HLA. 2020 Aug 22:10.1111/tan.14047. doi: 10.1111/tan.14047. Online ahead of print.

Novelli G, Novelli A, Borgiani P, Cocciadiferro D, Biancolella M, Agolini E, Pietrosanto M, Casalone R, Helmer-Citterich M(6), Giardina E, Jain SK, Wei W, Eng C, Pandolfi PP. WWP1 germline variants are associated with normocephalic autism spectrum disorder. Cell Death Dis. 2020 Jul 23;11(7):529.

Novelli A, Biancolella M, Borgiani P, Cocciadiferro D, Colona VL, D'Apice MR, Rogliani P, Zaffina S, Leonardis F, Campana A, Raponi M, Andreoni M, Grelli S, Novelli G. Analysis of ACE2 genetic variants in 131 Italian SARS-CoV-2-positive patients.Hum Genomics. 2020 Sep 11;14(1):29.

Floris A; Luo J; Frank J; Zhou J; Orrù S; Biancolella M; Pucci S; Orlandi A; Campagna P; BalzanoA; Ramani K; Tomasi M.L. Star-related lipid transfer protein 10 (STARD10): a novel key player in alcohol-induced breast cancer progression. J Exp Clin Cancer Res. 2019 Jan 5;38(1):4.

Pucci S.*, Polidoro C.*, Greggi C., Amati F., Morini E., Murdocca M., Biancolella M., Orlandi A., Sangiuolo F., Novelli G. Pro-oncogenic action of lox-1 and its splice variant lox- Δ4 in breast cancer  phenotypes. Cell Death & Disease.. 2019 Jan18;10(2):53.